Natural or herbal excipients are preferred over their synthetic counterparts because they are widely available, inexpensive, and non-toxic. The quality of the drug is partly affected by the quality of the excipients.The plant uses excipients, carrageenan, thaumatin, lard, stirax, agar, acacia and tragacanth as natural sources of its gum and mucilage. Additionally, they can be easily modified to meet specific needs, making them useful in providing standard pharmaceutical ingredients while complying with other pharmaceutical standards. The aim of this study is to reveal the potential of natural materials such as diluents, binders, disintegrants and lubricants in various formulation agents that are biocompatible and can provide additional nutrients to production materials. This article provides an overview of natural products used in new procedures and pharmaceuticals.This article gives an overview of natural Excipients used in drug distribution processes and prescriptions. Drug delivery is the process of administering drugs to humans or animals to produce therapeutic effects. The use of pulmonary and nasal delivery systems to treat human diseases has become important. Particularly for peptide and protein therapy, these delivery systems respect parental control. As a result, various drug delivery systems were developed and research on lung and nose diseases continued. Stringent requirements for this delivery system are demonstrated by biodegradable polymeric nanoparticles.