Original Review Article Volume 2 Issue 1
Original Review Article 2024 JAN-MAR 2024,367-378.
A REVIEW : ALOE VERA IS MIRACLE PLANT
Shirish B. Nagansurkar, Sanjay K Bais, Mustafa B. Mujawar
Fabtech College of Pharmacy, Sangola Corresponding author Mail ID: mustafamiujawar96@gmai.com
ABSTRACT :
Aloe vera is sometimes called the “miracle” or “wonder” plant because of the gel inside its fleshy leaves and has been used by humans to treat different diseases for centuries. Medicinal uses and uses of the main species, Aloe vera (L.) Burm. F. Often attributed to immunomodulatory or antioxidant activity. Our work in Vera began with the isolation of anthraquinone and continued with the purification. Natural treatments are more popular because they are safer and have fewer side effects than synthetic treatments. There is a growing demand for herbal preparations in the commercial world. Current research suggests that aloe vera, rose water, glycerine, soap-based almond oil, olive oil, etc. It includes the development and analysis of herbal facial treatments. Although there are many types of herbal medicines available in the market for acne treatment, our goal is to create herbal medicines without using synthetic ingredients. Ma king an herbal face wash with aloe vera is a good thing to try. The leaves of this beautiful plant contain many vitamins, minerals, natural sugars, enzymes, amino acids and many bioactive compounds with emollient, laxative, anti-inflammatory, antioxidant, antibacterial and antimicrobial properties. It has antifungal, aphrodisiac, antiseptic and cosmetic value. Although the instructions for use may differ, the results cannot be determined without clinical studies. The oldest and most widely used plant in the world is aloe vera, also known as Ghritkumari. It is a member of the Xanthorrhoeaceae family (APG III System, 2009). Since Rigveda’s time, aloe vera root has been utilized for therapeutic and health-related uses. Aloe vera can be used for many health purposes such as treating burns, wounds and frostbite; protect skin from X-ray damage; against stomach, gastric and blood cancer; and for high- and low-density lipoprotein (HDL).
Keywords: Chemical components, extraction of gel, processing, extraction of aloin.
Original Review Article 2024 JAN-MAR 2024,379-388.
REVIEW ON COMERERSIAL CULTIVATION AND COLLECTION ASPECTS OF MEDICINAL AND AROMATIC PLANTS
Amol V. Pore, Sanjay K. Bais, Sushmita S. Fate
Fabtech College of Pharmacy, Sangola
Corresponding author Mail ID: sushmita.fate02@gmail.com
ABSTRACT :
Nowadays, growing medicinal and aromatic plants (MAP) is not only advised in order to prevent wild plant gathering, but it also serves as a safeguard for the survival of damaged, disease-free plants from which disease-free seeds are unlikely to develop. It is also a strong industrial branch that provides quality raw materials to the pharmaceutical, cosmetics and food sectors. Many issues pertaining to the production, marketing, and fluctuating costs of small, medium, and big goods are encountered in the general cultivation of medicinal plants, which are primarily regarded as secondary crops. The herbal sector accepts Cultivation MAP information since it facilitates the estimation of plant quality, quality, and chemical content—particularly when contrasted to wild goods. The risk of plant misidentification and adulteration is removed when using farmed MAP data. The outcomes of chemical farming are contrasted with those of normal farming, which makes use of pesticides, fertilizers, specialized equipment, and techniques to manage insects, vermin, and insect stings. Low-cost monoammonium monophosphate cultivation is necessary to generate competitive, high-quality food from wild plants on the global market. The most frequent problems encountered by herbalists are financial, related to access and quantity of wildlife, the agricultural environment, energy and expenses, technological investment, post-harvest processing, and production results. The creation of superior plants depends on having ideal genotypes.
Keywords: cultivation, collection, drying, harvest, medicinal plants, plant growth hormones.
Original Review Article 2024 JAN-MAR 2024,389-406.
REVIEW ON SOME TYPICAL MEDICINAL PLANTS AND THEIR ACTIVE CONSTITUENT’S ABILITY FOR WOUND HEALING
Shirish B. Nagansurkar, Sanjay K Bais, Sakshi Shinde
Fabtech College of Pharmacy, Sangola
Corresponding author Mail ID: Sakshinshinde02@gmail.com
ABSTRACT :
A wound is a physical and functional reaction that occurs in the skin after an injury. The intricate process of restoring or repairing tissue after an injury is known as wound healing. A wound occurs when tissues that are alive, including skin, mucous membranes, and organs. An injury triggers a coordinated series of events that normally results in wound healing. The alleviate cascade occurs This causes platelets to accumulate and release the clotting process, eventually forming a fibrin clot at the site of injury. The fibrin clot acts as a cross-linking matrix, creating a framework for action during healing. A significant chunk of the world-wide medicinal market is made up of plant materials and herbs are important in many treatments. Throughout history, people have used plants and plant components to treat and control various ailments. Many kinds of biopolymers are currently being studied in order to create a stable, affordable, long lasting and efficient delivery system for wound care.
Key words: Disruption, herbal remedies, remodelling, coagulation
Original Review Article 2024 JAN-MAR 2024,407-417
REVIEW ON MOISTURIZING ACTIVITY OF HERBAL COLD CREAM FOR SKIN DRYNESS.
Yogesh B. Raut, Sanjay K Bais, Sahara chavan
Fabtech College of Pharmacy, Sangola
Corresponding author Mail ID: saharachavan1911@gmail.com
ABSTRACT :
Peeling, itching, and cracking of the skin are unpleasant symptoms of dry skin. It becomes dry when it loses water too quickly. Stated differently, the root cause of the issue is dehydration. Moisturizing Creams used for dry skin to prevent and cure it. They can also conceal flaws, enhance skin tone and texture, and shield delicate skin.The cream slows evaporation of water and provides a cooling and relaxing effect to the herbal extract incorporating cold cream. Since they create an oily barrier that stops water loss from the stratum corneum, the skin’s outermost layer, cold creams are more hydrating. Herbal remedies or their extracts have been marketed as cosmetics and topical preparations.It might be a viable natural remedy for the problem of dry skin.The study begins with an overview of the properties and benefits of herbal extract in skincare.
Key Words :- Dehydration,Moisturizing cream, Herbal remedies.
Original Review Article Jan Mar 2024,Vol 2 Issue 1,408-427
REVIEW ON GREEN CHEMISTRY AND CATALYSIS
S.R. Mane , Sanjay K. Bais, Aditya Arun Mali
Fabtech College of Pharmacy, Sangola
Corresponding author Mail ID: adityamali2907@gmail.com
ABSTRACT :
Sustainable chemistry, also referred to as Green chemistry refers to the development of chemical products and processes that reduce or eliminate the demand for hazardous materials.. Environmentally friendly chemical processes and products are their area of expertise. Its twelve guiding principles can be applied to create or duplicate dust particles, accessories, vaccinations, and procedures that are healthier, cleaner, and safer for human health. Green chemistry lessens theinfluence of chemical technologies and procedures, as the content demonstrates. The aim of this research is to learn more about the role of catalysts in the herbal mixture in creating the future. Catalysis is an important factor in the combination of new environmentally friendly materials and composites. The energy required for the catalytic process to produce small particles, aggregates, and additional waste points indicates efficiency. Catalysts that will not harm the soil can be created. Catalysts are available in many different shapes and forms, some of which are useful in the pharmaceutical industry.
Keywords:Biocatalysis, biomass, ionic liquid, critical, Microwave oven irradiation, photocatalysis and green chemistry definition of green chemistry Green chemistry: Biocatalysis, biomass, ionic liquid, critical Fluids, Microwave Irradiation, Photocatalytic Chemistry.
Original Review Article Jan Mar 2024,Vol 2 Issue 1,428-439
REVIEW ON RECENT ADVANCEMENT IN HERBAL TECHNOLOGY
Amol V. Pore, Sanjay K. Bais, Vaibhav J. Ghutukade
Fabtech College of Pharmacy, Sangola
Corresponding author Mail ID: vaibhavghutukade7212@gmail.com
ABSTRACT :
These days, individuals are growing more interested in herbal treatments because of their many advantages. Nowadays, many people acknowledge that using herbal treatments to cure various conditions can be successful. Over 80 percent of individuals worldwide rely on herbal goods as well as treatments for excellent health, even if the majority of these usage are un orthodox. Along with a rise in product adulteration and misuse, the growing popularity of herbal goods has frustrated producers, customers, and in some cases resulted in fatalities. The evolution of dependable, authentic analytical techniques that are able to characterize the phytochemical content is one of the main issues facing scientists. Among these methods are numerical evaluations of bioactive/ identifying substances and additional relevant components. The current review article describes a number of convectional approaches as well as more recent developments. DNA fingerprinting, metabolomics, chemometrics, X-ray diffraction, differential pulse polarography, and other recent developments are noted. It is also reported that chromatographic methods and capillary electrophoresis have contributed to the standardization of herbal medications.
Key words: Chromatographic techniques, Herbal medications, standardization, and DNA fingerprinting.
Original Review Article Jan Mar 2024,Vol 2 Issue 1,440-449
REVIEW ON DRUG EVALUATION METHODS
Amol V. Pore, Sanjay K. Bais, Shravani A. Mundhe.
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding author Mail ID: mundhe.shravani11@gmail.com
ABSTRACT :
Pharmacokinetics and pharmacodynamics of different drugs in adults and children are particularly heterogeneous in the latter. The differences between pharmacokinetics and pharmacodynamics prove unique studies but give rise to many ethical and practical issues. The main problems to be overcome when conducting clinical studies in children are the impact of the procedures and problems in patient recruitment. In general, the associated pain/anxiety and blood failure preclude pharmacokinetic studies in children, especially infants and young children. Population-based approaches based on pharmacokinetic-pharmacodynamic models are particularly attractive in children because these models can produce heterogeneous data. Quantitative/qualitative evaluation of the effects of studies on dose mixing and social interactions in societies and factors that may explain individual differences were noted.
KEYWORDS: Drug evaluation techniques, Pharmaceutical drug assessment, Drug efficacy evaluation, Safety evaluation methods for drugs, Preclinical drug evaluation.
Original Review Article Jan Mar 2024,Vol 2 Issue 1 450
The Pharmaceutical Industry’s Quality Assurance And Quality Control measures
Sanjay K. Bais, Akshada A. Pandit
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding email id: akshadaapandit7161@gmail.com
ABSTRACT :
Regulation as well as guarantee of excellence are the primary considerations .for the production, marketing, and distribution of pharmaceutical goods in order to guarantee their efficacy, safety, strength, and purity. The worldwide methods for evaluating the amount of residual solvents and different inorganic and organic contaminants in pharmaceuticals are briefly reviewed here. Due to national and international requirements, it is now required to provide both the purity profile and the impurity profile of a certain pharmaceutical product. Along with the importance of pharmaceutical quality, efficacy, and safety, these factors are also discussed, along with the types, sources, and controls of impurities as well as regulatory issues. .These days, providing both an impurity profile and a purity profile is required of a specific pharmaceutical product as a result of regional, national, and worldwide laws. These elements that are important in addition to the effectiveness, safety, and quality of pharmaceuticals, such as the types of impurities, their sources, their controls, and their regulatory aspects are talked about requirements to implement any nation’s medical system is the availability of essential medications in good quality, since substandard medications possess the capacity to do harm or even death of patients. Existence of undesirable substances in a specific medication even in minute concentration could impact its effectiveness and safety. Thus, quality use of pharmaceuticals has been a global concern that is currently receiving critical consideration from oversight bodies.[1]
Keywords: Quality System, Quality Assurance, Quality Control, Good Manufacturing Practices, Good Laboratory Practice, International Conference on Harmonization, International Organization for Standardization, Quality by Design, Calibration and Validation.
Original Review Article 2024 JAN-MAR 2024,456-464
REVIEW ON ADVANCE HERBAL TECHNOLOGY AS PER WHO GUIDELINES
Sarfaraz Kazi, Sanjay Bais, Purva Survase
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
corresponding author mail:- purvasurvase513@gmail.com
ABSTRACT :
Objective:-Learn first how to apply various techniques in different ways. Method:-Microwave extraction, Soxhlet extraction, Digestion, Infusion, and Maceration Exist Due to the many advantages of plants, there is a growing inclination among individuals to use them. It is now accepted that the use of plants is used in the treatment of many diseases. Despite some negative uses, the truth is that over 80% of the world’s population relies on herbal and medicinal products to maintain their health. The escalated utilisation of plants has also resulted in several instances of mistreatment and contamination, resulting in discontentment among consumers and producers, and in some circumstances, fatalities. A significant obstacle that scientists must overcome is the development of verified analytical techniques capable of determining the chemical makeup of phytochemicals. The approach should include thorough investigation of prescription medications/bioactive pharmaceuticals and other crucial variables. Design is essential for the development of effective services related to biological activity patterns, chemical profiles, and even the design and manufacturing of plants. This review article provides an overview of both conventional procedures and contemporary advancements.1 Result:-Medications made from herbs have the power to improve overall health and boost immunity while reducing negative effects, able to actually save the money. Conclusion:-Based on this analysis, we can infer that medicinal herbs are significant in our daily existence. The use of herbs to treat mild to moderate pain is common because they have no negative side effects.
Key word: Herbal medicine, Authentication, Extraction, Purification, Chromatographic technique.
Original Review Article 2024 JAN-MAR 2024,456-464
REVIEW ON BIOLOGICAL INDICATORS
Jyoti B. Salgar, Sanjay K. Bais, Reshma A. Mule
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding Author: reshmamue2001@gmail.com
ABSTRACT :
Objective:- The components, characteristics, and problems of bis are thoroughly examined in the first section of this article. Bis are trustworthy measuring instruments when used properly, however it has been shown that they are not ideal for use as standards. Since the goal of sterilization procedures is to eradicate germs, they must be validated in a way that highlights the role Bis plays in microbial mortality.
Method: The second section discusses the use of Bis in the specific sterilizing methods of radiation, ethylene oxide, wet heat or steam, and dry heat. There are suggestions given on how to use Bis in different procedures. Medical equipment producers invest a lot of time and resources in verifying and monitoring their processes to ensure that their goods are clean and safe. The confirmation study is the product of a multidisciplinary team effort.
Result: For this mission to be successful, every discipline needs To fully comprehend the foundations of every scientific field Then put those into practice principles Based on their individual technological knowledge. In order to assess the various technical sterilization approaches and biological indicators (Bis), this study attempts to convey the basic concepts of sterilization methodology.
Conclusion: These will primarily go over general sterilizing methods with a focus on their microbiological elements. The best place to start is by defining sterility and figuring out how to achieve it through BL validation trials.
Key Words: Sterilization, biological indicator, validation, and healthcare products
Key word: Herbal medicine, Authentication, Extraction, Purification, Chromatographic technique.
Original review Article,Vol 2,Issue 1
CULTIVATION AND COLLECTION ASPECTS OF MEDICINAL AND AROMATIC PLANTS – A COMMERCIAL APPROACH
Jyoti. I. Kalel, Sarfaraz. M. Kazi, Sanjay. K. Bais
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding author: Ms.Jyoti Kalel Mail.ID: jyotikalel1904@gmail.com
ABSTRACT :
Objective: This review provides a comprehensive overview of the cultivation, post-harvest technology, and good agricultural practices (GAP) for medicinal and aromatic plants. Methods: Emphasizing sustainable practices, it covers aspects such as site selection, soil preparation, harvesting techniques, post-harvest handling, storage, and regulatory compliance. The importance of ethical considerations, community engagement, and the economic impact of medicinal plants is highlighted
Result: Additionally, the review explores the conservation of medicinal plants through in-situ and ex-situ methods, habitat preservation, biodiversity conservation, and cultivation. It emphasizes the role of legislation, community involvement, and education in successful conservation efforts. A separate section delves into the economic contributions of medicinal plants, ranging from pharmaceuticals to tourism.
Conclusion:The multifaceted impact on national economies, employment, and biodiversity underscores the need for a balanced approach to harnessing the benefits of medicinal plants. In conclusion, the integration of sustainable cultivation practices, conservation efforts, and economic considerations offers a holistic framework for the responsible use and preservation of medicinal plants.
KEYWORDS: medicinal plants, Aromatic plants, vinca, GAP, in-situ, ex-situ, biodiversity conservation, regulatory requirement, altitude, collection.
Original review Article,Vol 2,Issue 1 ,495-509.
PERSPECTIVES IN ANTI-ACNE STRATEGIES: A COMPREHENSIVE OVERVIEW
Sarfaraz Kazi, Sanjay Bais, Akshata Chopade
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
Acne, a multifactorial skin disorder affecting individuals globally, presents both physical and psychological challenges.This abstract provides a comprehensive examination of current perspectives, advancements, and general information regarding anti-acne strategies. Traditional treatments, encompassing topical retinoids, antibiotics, and systemic therapies, have laid the foundation for addressing acne. Recent research sheds light on the genetic and molecular aspects of acne, fostering the emergence of precision medicine for personalized interventions. The intricate relationship between the skin microbiome and acne pathogenesis is a focal point of exploration, offering new avenues formicrobiome-modulating therapies. Advances in topical formulations, including microencapsulation technologies, promise improved drug delivery and efficacy. Biologics, hormonal therapies, and botanical extracts represent evolving dimensions in acne therapeutics, showcasing diverse mechanisms of action.
Keywords: Acne vulgaris, retenoids, antibiotics,lesser and light,Traditional treatments, systemic therapies, microbiome-modulating therapies, micro-encapsulation.
Original review Article,Vol 2,Issue 1 ,510-517.
A REVIEW: – FORMULATION AND EVALUATION OF HERBAL LOTION
Shubhangi Pawar, Sanjay K Bais, Dipali Bandawade.
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
The demand for standardization and the makeup of herbal products in daily life are the main topics of this essay. The best results in our daily lives will come from the composition of herbal products, as the Composition of each unique product on its own. Applying lotions straight to the body results in their semi-liquid form. Moisturizing lotion is a semisolid preparation that fights wrinkles and lowers the risk of skin issues.There were no negative effects from the herbal lotion composition. Aloe Vera gel and honey are combined to create a herbal lotion that not only nourishes skin but also functions as an antioxidant, antibacterial, and anti-inflammatory. The manufactured lotion is regularly tested for irritation, acidity, and pH. Aloe Vera gel’s moisturizing properties are used to prevent sunburn and acne in addition to preventing dry skin in the summer and winter. The herbal lotion is safe to use on skin because it passes all assessment tests and has no negative effects Key Words: –Herbal lotion, Honey, Aloe Vera gel, Coconut milk.
Original review Article,Vol 2,Issue 1 ,518-530
A REVIEW: PREPARATION AND EVOLUTION OF HERBAL MOUTHWASH
Srinivas R.Mane, Sanjay K Bais, Sandesh S. Akade
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
Several types of microorganisms call the mouth cavity home. While certain kinds of oral bacteria are benign, there are also those that can cause oral plaque, pathetic breath, and mouth diseases. Consequently, maintaining proper dental hygiene is crucial for a healthy mouth and body. Herbs are extremely valued for their effectiveness when compared to chemical products. Because of its longlasting Medicinal plants with antibacterial and antifungal properties against human pathogens are crucial for the treatment of a number of illnesses. Herbal products aid in reducing dental plaque, preventing bacterial growth, improving breath quality, and cleaning teeth. You can use herbal mouthwashes. in addition other dental health procedures such as flossing and cleaning your teeth. Because of their potent anti-inflammatory and anti-plaque characteristics, they applied in periodontal treatment with support. Many herbal products and their respective extracts, including peppermint, Turmeric and neem , and cloves possess demonstrated notable benefits. more so than chemical ones Because of their long-lasting anti-bacterial, antimicrobial, and anti-fungal effects on human pathogens, medicinal plants are essential for the treatment of disease. There could be a lot of benefits to using natural mouthwash instead of conventional ones. If a formulation like this could be created that individuals could safely and readily prepare utilizing at home organic products. Keywords: – Herbal mouthwash ,Herbal natural exctrat ,Neem ,Clove.
Original Review Article Vol 2 Issue 1, 546-560
REVIEW ON NOVEL HERBAL DRUG DELIVERY SYSTEM
Sanjay.K.Bais, Sakshi.S.Todkari.
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
A revolutionary approach to drug distribution, NDDS overcomes drawbacks of the conventional drug delivery methods. NHDDS come in a variety of forms, phytosomes, liposomes, niosomes, proniosomes, transfersomes, ethosomes, nanoparticles, and microspheres. When new medication delivery technology is used in herbal therapy, it may help different herbal compounds and herbs work more effectively and have fewer negative effects.This is the main concept behind adding cutting-edge drug delivery techniques to herbal remedies. To tackle more serious ailments, it is crucial to combine Indian Ayurvedic remedies with innovative drug delivery systems. In order to obtain modified delivery of herbal medications, novel drug delivery systems have become increasingly important. This has increased the therapeutic value of these drugs while lowering their toxicity. In order to improve treatment response, new drug delivery systems have been created, which are summarised in this arti cle and used to deliver herbal medications. KEYWORDS: Herbal medicine, novel drug delivery system.
Original Review Article Vol 2 Issue 1, 561-573
A REVIEW: DEMONSTRATING THE ETERNAL ACTIVITY OF A FACE WASH MADE WITH HERBAL PLANTS
Sanjay K.Bais, Jyoti Dum
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
The purpose of this study is to create and assess a herbal face wash that will help with acne and brighten and cleanse the skin. The following ingredients are used: vetiver, also known as Usheer or Khus (skin whitener); Rubia cordifolia, also known as Manjistha (blood purifier and skin glowing); pineapple & lemon (dark spot remover); Tulsi; honey; turmeric; aloevera; neem; rose water; propyl paraben; methyl paraben; and sodium lauryl sulfate. The combination of herbs is leading to an increase in demand on the global market. The plants’ microbes, antioxidants, and anti-inflammatory properties have all been documented in the literature. People can use a variety of beauty products on a regular basis these days, especially ladies. The use of herbs for medicinal purposes was mentioned in the Vedas, and Ayurveda and Unani, two ancient healing recovery methods, are utilized. Keywords: natural components, acne, skin care, dullness of the skin, etc.
Original Review Article Vol 2 Issue 1, 574-584.
REVIEW: HERBAL PLANTS USED IN THE SUNSCREEN
Yogesh B. Raut ,Sanjay K Bais, Kunal Ghodake .
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
Sunscreen is a chemical substance that aids in UV radiation protection. UV B radiation is what causes sunburn, while UV A may do greater harm to the skin. The optimal sunscreen should obstruct both wavebands. The purpose of this study was to create a topical herbal sunscreen formulation using a mix of medicinal herbs and certain fixed oils. The development of melanoma, squamous cell carcinoma, and actinic keratosis is decreased by regular use of sunscreen. Chemicals in sunscreen can be either organic or inorganic. Sunblock lotion is another name for sunscreen. The product that shields skin from UV rays of the sun by reflecting or absorbing them. Sunscreen use has grown because of the rising prevalence of skin cancer and the photo damaging effects of UV radiation. Sunscreen ingredients should be completely safe, chemically inert, non-irritating, non-toxic, photo stable, and able to shield the skin from sun harm. Key words: radiation, carcinoma, obstruct, non-irritating.
Original Review Article Vol 2 Issue 1, 585-602.
REVIEW ON HERBAL PLANTS AND THEIR ACTIVE CONSTITUENTS IN TREATMENT OF ALZHEIMER’S DISEASE.
Jiwan P.Lavande Sanjay K Bais, Sakshi Rayban
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
The most frequent kind of dementia is Alzheimer’s disease, a neurological disorder. that progresses over time and affects over 10 million individuals worldwide. It was first published in 1906 by Alois Alzheimer, who wrote on a patient he had seen in 1901. A neurological disease that is complex, progressive, and Alzheimer’s is characterized by changes in personality, memory loss, and a decrease in mental abilities. A number of medical systems, most notably the Unani system, have employed medicinal plants, which have proven to be effective in treating and managing memory problems. The neuroprotective properties of these herbs are then explained by the bioactive components. Alkaloids, polyphones, terpenoids, and flavonoids are among the compounds being investigated for their potential to reduce oxidative stress, reduce neuro-inflammation, and alter important molecular pathways connected to the pathophysiology of Alzheimer’s disease. Clinical experiments have confirmed the efficacy of most herbs and plants, and their chemical evaluation has also been completed. Still, the fundamental workings of acts are not fully understood. Herbal and medicinal plant remedies are becoming more popular as complementary and alternative therapies.The role of bioactive components in neurodegenerative herbs and their significance for loss of memory connected to Alzheimer’s and Before Alzheimer’s is reviewed in-depth in this article based on a systematic review of recent research. The paper covers the probable mechanisms of action for these herbal ingredients’ therapeutic benefits, such as antioxidant activity, anti-inflammatory characteristics, cholinesterase inhibition, and neurotransmitter system regulation. Keywords:- Alzheimer’s disease, dementia, neurological disease, herb.
Original Review Article Vol 2 Issue 1, 603-611
AN ANALYSIS OF MODERN HERBAL TECHNOLOGY
Sarfaraz Kazi, Sanjay Bais, Pratikasha Shinde.
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
Objective: First, learn about the different ways to use different techniques. Methods: Maceration, Infusion, Digestion, Soxhlet extraction, Microwave extraction. The growth of herbal products has also led to the emergence of some dangerous ideas and products that have surprised consumers and manufacturers, some with major consequences. Developing a realistic method that can characterize the chemical composition of plants is a difficult task for scientists, including many studies on paper/bioactive composites and other important factor. Standardization is an important step in the effort to create harmonious and compatible medicine in every field, from direct safety programs to herbal products and manufacturing. A growing number of experimenters have proposed a number of fresh concepts and technological breakthroughs as a result of the lightning-fast development of logical procedures and the rising awareness for the quality of natural sources. The essential concepts, distinctive qualities, and practical applications of chemical and natural assessments, as well as how these components work together to judge the calibre and thickness of natural sources, are the main subjects of this examination. Result: Herbal medications have the potential to decrease adverse impacts and promote self healing. Conclusion: From this review we can conclude that medicinal herb play an important role in our lives. Herbs are often used as a side-effect-free method to treat mild to moderate pain. Keywords: Chromatographic techniques, Extraction, Purification, Authentication, Standardization, Pharmacological effects, Evaluation, Herbal medicine, soxhlet, infusion, Digestion.
Original Review Article Vol 2 Issue 1, 612-624
HERBAL FACE SCRUB FOR SKIN EXFOLIATION
Jyoti.B.Salgar, Sanjay.K.Bais and Priyanka S. Godase
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
Scrubs are products used to remove dead cells, pigmentation, blackheads and whiteheads from the skin, making the skin bright, smooth, soft and healthy. Toothpaste can be used directly on the skin. In today’s society, masks are very popular, cheapersuccessful. Natural or herbal cosmetics are made using natural substances to treat wrinkles, acne, and oil secretion management. skin dryness after prolonged usage, which shortens the duration of acne and redness. Using a scrub Antimicrobial, antioxidant, and anti-aging plant parts are typically found in herbal cosmeceuticals. Cosmetically are products that affect the biological function of the skin, and herbal cosmetics are the safest to use regularly.The main purpose of this study is to prepare different types of herbal cosmetics Natural or herbal cosmetics work by using natural components to reduce oil production, treat wrinkles, and treat acne. Herbal cosmetics often contain herbs with qualities that are antibacterial, antioxidant, and anti-aging Cosmetics are the safest things to use on a regular basis and have no negative effects; yet, they alter the biological activities of the skin. In this preparation, the active ingredients in the gel preparation with The ingredients in carbopol include glycerin, sodium lauryl sulfate, methyl paraben, turmeric, aloe vera gel, coffee, coconut oil, rose water, and fenugreek. Differences The main purpose of this study is to prepare different types of herbal cosmetics in gel form. Keywords: antioxidant, skin, acne, exfoliants, phyto ingredients, herbal scrub.
Original Review Article Vol 2 Issue 1, 625-639
A REVIEW: – ROLE OF AYURVEDA IN EPILEPSY
Ashwini Zade, Sanjay K. Bais, Irshad. I. Nadaf
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
The article explores the role of Ayurveda in the comprehensive management of epilepsy, providing a nuanced understanding of its ancient wisdom and integration with modern medical practices. Beginning with an introduction to epilepsy and its current treatment challenges, the review delves into the Ayurvedic conceptualization of the disorder, emphasizing the doshic imbalances, particularly involving the Vata dosha. The historical roots of Ayurveda’s engagement with neurological disorders, including epilepsy, are examined, highlighting the evolution and adaptability of this ancient healing system. The article elucidates Ayurvedic diagnostic methods, incorporating pulse diagnosis, tongue examination, and individualized assessments based on prakriti and vikriti analyses. Subsequently, Ayurvedic treatment modalities are expounded, encompassing herbal formulations, dietary recommendations, lifestyle modifications, and traditional detoxification therapies. The integration of Ayurveda with modern medicine emerges as a focal point, emphasizing collaborative care, diagnostic synergy, and personalized treatment plans. Safety considerations in Ayurvedic epilepsy management are addressed, acknowledging the importance of quality control, individualized assessment, and collaborative monitoring. Keyword :- Ayurveda offers seizure management through herbal remedies, lifestyle modifications, Panchakarma therapy, Nadi Pariksha, Ayurvedic diet, and therapies.
Original Review Article Vol 2 Issue 1, 640-654.
STAGES OF THE SALES CYCLE IN PHARMACEUTICALS
Jyoti B. Salgar, Sanjay K. Bais, Tanjeel S. Mulani
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
This comprehensive review explores the intricate stages of the pharmaceutical sales cycle, dissecting each phase’s significance and the challenges encountered in this dynamic industry. Beginning with lead list preparation, the foundation of success, the journey unfolds through stages like first contact/interview, funnelling customers, and in-depth product discussions. Each stage requires a nuanced understanding of the pharmaceutical landscape, regulatory frameworks, and the unique needs of healthcare professionals. Addressing customer objections emerges as a pivotal aspect, where pharmaceutical sales representatives employ strategic finesse to overcome concerns related to product efficacy, safety, pricing, and competition. Negotiations and sales closing follow, demanding a delicate balance between assertiveness and collaboration, emphasizing the need for adherence to regulatory standards and alignment with client objectives. The review then delves into the strategic generation of referrals, recognizing the power of satisfied clients and professional networks in expanding pharmaceutical reach. Lastly, the challenges inherent in pharmaceutical sales, encompassing government intervention, intense competition, precise target assessment, adherence, compliance, and technological advancements, are explored. These challenges necessitate adaptability, regulatory acumen, and strategic thinking for successful navigation. Keywords: Pharmaceutical Sales, Sales Cycle, Lead List Preparation, Customer Interactions, Funneling Strategies, Product Discussions, Customer Objections Handling, Negotiations.
Original Review Article Vol 2 Issue 1, 655-667
A REVIEW: – APPICATION OF AI IN PHARMACEUTICAL SCIENCE
Ashwini Zade, Sanjay K. Bais, Simran A. Nadaf
Fabtech College of Pharmacy, Sangola, Dist. Solapur, Maharashtra, India.
Corresponding by: akshatachopade@gmail.com
ABSTRACT :
This review delves into the transformative influence of Artificial Intelligence (AI) in pharmaceutical science, with a primary focus on accelerating drug discovery processes. AI’s capacity to analyze vast datasets, encompassing genomic information and chemical structures, emerges as a game-changer, significantly outpacing traditional methods. The article explores key areas such as target identification, validation, predictive analytics for drug development, personalized medicine, and the optimization of clinical trials.AI’s data-processing capabilities streamline drug discovery by efficiently pinpointing potential drug candidates and expediting the validation of targets. The integration of predictive analytics enhances decision-making in drug development, minimizing trial failures and prioritizing compounds with higher success probabilities. The paradigm shift towards personalized medicine is examined, showcasing how AI tailors treatments based on individual patient data for improved efficacy. Furthermore, the article delves into the optimization of clinical trials, emphasizing AI’s role in enhancing trial design and patient cohort selection. By offering a comprehensive overview, this review underscores the profound impact of AI on reshaping pharmaceutical science, fostering more efficient, targeted, and patient-centric approaches to drug discovery.
Al pharmaceutical science utilizes predictive modeling, data analysis, and precision medicine for drug discovery, clinical trial optimization, and personalized treatment.