Mimosa Pudica, commonly known as the "sensitive plant" or "touch-me-not," holds significant ethno-botanical importance and has garnered attention for its pharmacological potential. This review provides an overview of the ethno-botanical uses and pharmacological properties of Mimosa Pudica. Mimosa Pudica has a rich history of traditional medicinal uses across various cultures. Pharmacological investigations have demonstrated diverse activities of Mimosa Pudica extracts and isolated compounds, including anti-inflammatory, antioxidant, antimicrobial, antidiarrheal, analgesic, antipyretic, wound healing, and neuroprotective effects. These findings suggest the therapeutic potential of Mimosa Pudica in managing various diseases and health conditions. Mimosa Pudica stands as a promising botanical species with ethno-botanical uses deeply rooted in traditional medicine and a growing body of scientific evidence supporting its pharmacological potential. Further research is warranted to elucidate the mechanisms of action, optimize dosages, and explore its clinical applications. Integration of traditional knowledge with modern scientific approaches may lead to the development of novel therapeutic agents derived from Mimosa Pudica for the benefit of global health and wellness.