FREQUENCY : QUARTERLY
PUBLISHER : ANANDI HEALCARE LLP,WASHIM-444505
CHIEF EDITOR : Dr. SANJAY K BAIS
COPYRIGHT : INTERNATIONAL JOURNAL OF PHARMACY AND HERBAL TECHNOLOGY
STARTING YEAR : 2023
SUBJECT : MEDICAL SCIENCES
LANGUAGE : ENGLISH
PUBLICATION FORMAT : ONLINE
PHONE NO : 8233000887
EMAIL ID : editorijpht@gmail.com
WEBSITE : www.ijprdjournal.com
ADDRESS : Near Kaleshwwar Mandir Shukrawar peth, Washim-444505 Maharashtra
Author Name: Suraj U. Kamble, Sanjay K. Bais, Tanjeel S. Mulani
Email: tanjilmulani0204@gmail.com
College: Fabtech College of Pharmacy, Sangola, Maharashtra1699-1709
This study focuses on the formulation and evaluation of ginseng granules aimed at providing antidiabetic activity. Ginseng, a well-known medicinal herb, is recognized for its potential benefits in managing diabetes due to its bioactive compounds, such as ginsenosides. The research involved preparing granules using a standardized extract of ginseng, followed by rigorous evaluation of their physical and chemical properties, including flowability, compressibility, and stability. In vitro assays were conducted to assess the granules ability to inhibit α-glucosidase and the enzyme α-amylase is involved in the metabolism of carbs. Additionally, in vivo studies on diabetic rats were performed to observe the hypoglycaemic effects of the ginseng granules. The outcomes showed that the ginseng granules that were prepared had a notable amount of enzyme inhibitory action and successfully lowered blood sugar levels in rats with diabetes, indicating that they could be used as an adjunctive treatment for diabetes control. This formulation could offer a novel, practical approach to harnessing ginsengs antidiabetic properties.
Ginseng, Granules, Antidiabetic activity, Herbal medicine, Diabetes management, Formulation development, Blood glucose levels, Insulin sensitivity, pharmaceutical excipients, Bioavailability, Traditional medicine.