Pharmacovigilance is the science & activities involved in identifying recognizing, assessing, checking, & preventing adverse effect of pharmaceutical products. Pharmacovigilance is the science & activities of pharmacists, crucial in maintaining safe &reasonable medicine use. This study examines the perspective of drug store students on pharmacovigilance & ADR Announcement in under graduate drug store education. Clinical Research encompasses the entire process from lab to consumer market, identifying promising drug. Pre-clinical studies or animal studies examine safety, toxicity, & efficacy. Pharmacovigilance is crucial in healthcare, assessing drug interactions & their effect on human. Pharmacogenetics & pharmacogenomics are essential in Clinical Research, as they determine human genome variation & disease susceptibility, aiding early drug discovery. Pharmacovigilance is crucial tool used to monitor the side effects & related problems of medicines & vaccines, ensuring their safety & effectiveness in the market. The relevant details are presented in this Chapter.