TDDS also traditionally called as patches. Due of their remarkable medicinal properties and minimal side effects as compared to synthetic drugs, the usage of herbal bioactive has grown recently on a global scale. In order to improve therapeutic response. The purpose of this review is to give a broad overview of the several innovative techniques that have been developed for the transdermal and dermal delivery of herbal medicines. Drug delivery systems involve the topical administration of medications. Pharmaceutical preparations known as transdermal patches come in a range of sizes and are designed to be applied to intact skin to transfer active ingredients into the bloodstream after they have passed through the skins barriers and prevented from having a first-pass effect. This review explores the role of various herbal drugs in TDDS, focusing on their bioactive compounds, therapeutic potential and advancements in formulation approaches. Key topics include skin permeability challenges, penetration enhancement strategies and the stability of herbal compounds in transdermal formulations. Novel techniques such as nanotechnology, liposomes and polymer-based carriers are discussed as methods to improve the efficiency of herbal transdermal systems. Herbal drugs hold significant potential in transdermal drug delivery due to their therapeutic benefits and natural origin. It is especially utilised when the liver has a large first-pass effect that can cause medications to be metabolised too soon. A viable and alluring method of administering peptides and proteins is transdermal distribution.