Although herbal medications are widely used due to their medical benefits, concerns regarding contamination have recently arisen. This review examines potential contaminants in herbal products, including pesticides, heavy metals, microbial illnesses, and adulterants. The implications for safety and effectiveness are discussed, highlighting the need for stringent qualifying control protocols. Herbal remedies can be rendered less safe and effective by contaminants such pesticides, heavy metals, microbiological infections, and adulterants. The origins and kinds of possible contaminants that may be present in herbal medicines are highlighted in this review article, along with their potential health consequences. It examines the pathways—agricultural practices, processing techniques, and storage conditions—through which these pollutants may infiltrate herbal products. The article also covers quality control procedures and regulatory frameworks that can reduce the danger of contamination. This study attempts to educate stakeholders, including consumers, manufacturers, and regulatory agencies, on the vital need for safe and effective herbal medicines by highlighting the significance of stringent testing and standardization.