The use of natural products in drug development and research is expanding. Because of the differences in their chemical composition, they can have an impact on several targets simultaneously in a complex system. Over the past ten years, there has been a significant advancement in the technology of natural drugs. The safety of herbal medicines may be clarified by looking into historical traditional medical practices. Now is the time to decide what products made with herbal medicine are safe and effective. herbal medicines reginonal variation exist in endorsement procedure as well as permitted grade. Global harmonisation is contingent upon the World Health Organisation has established exact strategies intended for assessing the efficacy, security, and calibre of herbs. The progress of science and technology encroaches on herbal remedies. DNA fingerprinting, metabolomics, chemometrics, X-ray diffraction, differential pulse polarography, and other recent developments are noted. Chromatography methods and capillary electrophoresis. There are also reports of contributions made to the standardisation of herbal medicines.