This review examines and summarizes the creation, characteristics, attributes, and uses of nanoemulsions. Submicron-sized emulsions known as nanoemulsions.Using the right surfactant, two nonreactive liquids (oil and water) come together to form a phase in a thermodynamically stable isotropic process called nanoemulsion. Due to their small size, nanoemulsion is stable against emulsification or precipitation; The main mechanism of nanoemulsion decomposition is Ostwald ripening.The diameter and surface area of nanoemulsion droplet are have a significant impact on the biological behavior of formulation. Future development in drug therapy, cosmetic, diagnostic, and biotechnologie all seem very promising when it comes to nanoemulsion. The purpose of this review is to discuss the advantage and disadvantage of nanoemulsion, including different preparation method, characterization methods, and application of submicron emulsions in various fields such as pharmaceutical cosmetics, chemotherapy, and other administration methods.