Accidental and perhaps dangerous side effects that arise from the inhalation of drugs are known as adverse drug reactions, or ADRs. This extensive study seeks to offer a complete analysis of the several aspects related to adverse drug reactions (ADRs), highlighting the importance of these events in maintaining patient safety and improving healthcare outcomes. In order to distinguish between predictable, dose-dependent effects and unpredictable, idiosyncratic responses, the review classifies ADRs into two categories: Type A and types B reactions. Typical instances of adverse drug reactions (ADRs) in several organ systems are examined, emphasizing the variety of ways that drugs can cause side effects. Reporting and monitoring of ADRs are discussed, emphasizing the crucial role of healthcare professionals in contributing to pharmacovigilance systems. The review underscores the importance of identifying patient-specific risk factors, such as age, gender, genetics, and concomitant diseases, to assess the likelihood of ADR occurrence.