FREQUENCY : QUARTERLY
PUBLISHER : ANANDI HEALCARE LLP,WASHIM-444505
CHIEF EDITOR : Dr. SANJAY K BAIS
COPYRIGHT : INTERNATIONAL JOURNAL OF PHARMACY AND HERBAL TECHNOLOGY
STARTING YEAR : 2023
SUBJECT : MEDICAL SCIENCES
LANGUAGE : ENGLISH
PUBLICATION FORMAT : ONLINE
PHONE NO : 8233000887
EMAIL ID : editorijpht@gmail.com
WEBSITE : www.ijprdjournal.com
ADDRESS : Near Kaleshwwar Mandir Shukrawar peth, Washim-444505 Maharashtra
Author Name: Mustafa B. Mujawar, * Shirish B. Nagansurkar, Sanjay K Bais
Email: mustafamiujawar96@gmai.com
College: Fabtech College of Pharmacy, Sangola, Maharashtra1871-1878
Two popular natural treatments drug for the treatment for constipation are Aloe vera juice and castor oil. Chronic constipation is a prevalent gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. Traditional remedies such as Aloe Vera juice and castor oil have been utilized for their laxative properties .The emulsion formulation was prepared using Aloe Vera juice, castor oil, emulsifiers, and stabilizers through a homogenization process. Various physicochemical parameters including, pH, stability, were evaluated to optimize the formulation. In vitro evaluations were conducted to assess the emulsions potential as a laxative, including its ability to stimulate bowel movement and its effect on intestinal motility. We study on the goat ilium by using student organ bath. Result may show the result have shown peristalsis movement and time of with drug without drug is 2.5min 8min respectively. The experiment demonstrated that the emulsion formulation exhibited desirable physicochemical properties. In vitro studies revealed that the emulsion effectively stimulated bowel movement, promoting peristalsis and facilitating stool passage.
constipation, peristalsis movement, stimulant laxatives, Purgatives.