The cosmetics are made entirely of natural substances; they do not contain any synthetic elements that could damage skin. The majority of hand sanitizers available in the market are alcohol-based hand antiseptics, which may have negative effects. Antibiotics may result in dermatitis, dryness, irritation, and itching. It works well against. Skin samples from volunteers were tested with various antibiotics, and the outcomes were inspected in containers. Because of the botanical qualities in the extract, the cup and saucer method findings demonstrated the effectiveness of hand antiseptics made with ginger alcohol extract and ginger aqueous extract. According to recent research, using herbs and incorporating them into recipes can improve outcomes. Antibiotics include chemical characteristics such as pH, viscosity, foam height, and foam retention in addition to physical characteristics including colour and odour. Two hand disinfection formulations were assessed according to their physical attributes, pH, and viscosity. The purpose of this research is to create hand sanitizer using ginger ethanol extract.