Innovative herbal formulations such as polymeric nanoparticles, nano capsules, liposome, Phytosomes, animations, microspheres, transferosomes, and ethosomes were made possible by proactive plant choices. It is claimed that compared to conventional formulations, the novel plant actives and extract formulations have significant benefits in terms of solubility, bioavailability, and safety from toxic effects, greater stability, heightened pharmaceutical efficacy, improved tissue macrophage dispersion, extended management, and immunity from physical and chemical degradation. A well-known manufacturer of pharmaceuticals and nutraceuticals invented the patented process known as "Phytosome," which combines phospholipids to lipid-compatible molecular complexes with water-soluble phytoconstituents or standardized plant extracts. By mixing the natural medications into modern dose forms, they can be taken more correctly and with more efficacy. Creating innovative medicine delivery methods using herbal ingredients can help attain this. The current study describes the current status of developing novel herbal formulations, summarises the biological function of several types of active ingredients, and discusses the applications of these compositions.