In the pharmaceutical industry, known for its complexity and competition, effective sales and marketing are important to ensure that doctors and patients are introduced to new drugs. This comprehensive review explores all aspects of sales and marketing in the pharmaceutical industry. These ideas are important for building relationships with doctors and hospitals, providing important information about products, and adapting to the digital-centric age. In business, this review looks at the complexities of direct-to-consumer (DTC) advertising, clinical education and research collaboration, research, and the use of advertising and marketing. He added that the rules must be clear and strictly followed when using this business strategy. Oversee business issues such as legal compliance and address the need for good business practices. Regulatory agencies, particularly the US FDA, play an important role in ensuring the integrity of marketing and advertising campaigns. The review highlights key sales strategies, including the role of the salesperson, key account management, and the growth of digital sales and expansion into electronic sales the mechanics of the pharmaceutical industry are changing at an incredible pace. Millions of dollars are spent on drug research, followed by a rigorous evaluation process, and eventually approved by drug regulatory authorities, allowing the drug to enter the market. Therefore, the cycle time of the drug development process is 10-15 years. A lot of money is spent on marketing these drugs to promote sales.