FREQUENCY : QUARTERLY
PUBLISHER : ANANDI HEALCARE LLP,WASHIM-444505
CHIEF EDITOR : Dr. SANJAY K BAIS
COPYRIGHT : INTERNATIONAL JOURNAL OF PHARMACY AND HERBAL TECHNOLOGY
STARTING YEAR : 2023
SUBJECT : MEDICAL SCIENCES
LANGUAGE : ENGLISH
PUBLICATION FORMAT : ONLINE
PHONE NO : 8233000887
EMAIL ID : editorijpht@gmail.com
WEBSITE : www.ijprdjournal.com
ADDRESS : Near Kaleshwwar Mandir Shukrawar peth, Washim-444505 Maharashtra
Author Name: Samruddhi Swami, * Yogesh Raut, Sanjay K. Bais
Email: yraut15@gmail.com
College: Fabtech College of Pharmacy, Sangola, Maharashtra 2100-2106
The current studys in-vitro anti-obesity efficacy is focused on the formulation creation and assessment of effervescent granules manufactured using a herbal extract mixture (a combination of raw Coffee arabica L. beans, Achyranthes aspera seeds, and hydro-alcoholic extract of Garcinia indica fruits). The soxhlet extraction method was used to extract all 3 plant components hydro-alcoholically. The bulk density, tap density, cars index, hausners ratio, angle of repose, and length of the effervescent cessation were all measured and evaluated for the effervescent granules. The physical characteristics of each batch were satisfactory. Additionally, the in- vitro lipase and α-amylase inhibitory activities of the herbal extract combination were examined at different concentrations (50, 100, 150, 200, 250, and 300) µg/ml. The herbal extract mixture had the highest inhibitory action against lipase and amylase at a concentration of 300 µg/ml, exhibiting 83.32± 10.47 and 69.14± 7.22, respectively. The results of this study might be useful in the future for formulating effervescent products made using plant extracts.
Amylase, Pancreatic lipase, Effervescent granules, Herbal extract mixture