Peptic ulcer is a common gastrointestinal disorder, is commonly caused by high gastric acid output, Helicobacter pylori or Helicobacter infection and usage of nonsteroidal anti-inflammatory drugs throughout Representative medicines (NSAIDs). Traditional therapies such as antibiotics and proton pump inhibitors (PPIs) may cause side effects and drug resistance. Often caused by an infection with H. pylori, long-term NSAID usage or excessive acid secretion, Peptic ulcers are a right gastrointestinal ailment defined to damage gastrointestinal / duodenal mucosa. Interest in alternative medicines has grown as a result of the potential side effects and complications associated with conventional treatments, notwithstanding their effectiveness. With a focus on their safety profiles, therapeutic efficacy and mechanisms of action, this review investigates the potential of herb treatments in the treatment of peptic ulcers. Herbal remedies have been used traditionally in many medical systems and because of their many different mechanisms of action, which include antioxidant activity, anti-inflammatory effects, improved mucosal protection, decreased gastric acid secretion and antimicrobial properties, they offer promising alternatives to conventional therapies. This research investigates the effects of peptic ulcer treatment on medicinal plants such as Aloe vera (Aloe barbadensis miller), Neem (Azadirachta indica), liquorice (Glycyrrhiza glabra) , papaya (Papaya Carica) , Ginger, Garlic, Mango, Drum Stick Honey, Banana, custard Apple, Acacia arabica and Indian berry. Their capacity to shield the stomach lining, encourage ulcer healing and fight H. pylori is supported by preclinical investigations. Still, more thorough clinical trials are required to verify their safety and efficacy, despite the positive results. A potential option for the comprehensive care of PUD is the use of herbal remedies, which are more affordable and have a lesser chance of adverse effects.