FREQUENCY : QUARTERLY
PUBLISHER : ANANDI HEALCARE LLP,WASHIM-444505
CHIEF EDITOR : Dr. Prashant Sakharkar
COPYRIGHT : INTERNATIONAL JOURNAL OF PHARMACY AND HERBAL TECHNOLOGY
STARTING YEAR : 2023
SUBJECT : MEDICAL SCIENCES
LANGUAGE : ENGLISH
PUBLICATION FORMAT : ONLINE
PHONE NO : +91 9172954046
EMAIL ID : editorijpht@gmail.com
WEBSITE : www.ijprdjournal.com
ADDRESS : Near Kaleshwwar Mandir Shukrawar peth, Washim-444505 Maharashtra
Author Name: Ujwala Umbarje, * Yogesh B. Raut, Sanjay K. Bais
Email: ujwalaumbarje60@gmail.com
College: Fabtech College of Pharmacy, Sangola, Maharashtra 2549-2568
A serious worldwide health issue today is diabetes mellitus, a long-term metabolic condition characterized by high blood sugar. Insulin and oral hypoglycaemic medications are examples of conventional treatment methods; however, they are frequently linked to long-term problems and adverse consequences. Because of their effectiveness, low cost and lack of negative effects, herbal medicinal plants have drawn interest as alternate or additional medications for the management of diabetes in recent years. This review examines the possible therapeutic benefits, mechanisms of action and active ingredients of several herbal plants in the treatment of diabetes. Through improvements in insulin sensitivity, increased production of insulin and inhibiting glucose absorption, a few plants, including Momordica Charentes (bitter melon), Trigonella frenum-graecum (fenugreek), Cinnamomum verum (cinnamon) and Gymnemate Sylvester, have demonstrated promising anti-diabetic properties. Many phytochemicals located in herbal medicinal plants, especially phenolic, alkaloids, terpenes and flavonoids, have been associated with antidiabetic effects by a variety of mechanisms. These include increased insulin secretion, decreased absorption of glucose and digestion of carbohydrates, increased Radial tissue glucose absorption and antioxidant reactions that reduce one of the main causes of diabetes is oxidative stress. In preclinical as well as clinical research, Trigonella frenum-graecum (fenugreek) and Momordica Charentes (bitter melon) are examples of plants Cinnamomum verum (cinnamon) and Gymnemate Sylvester indicate great potential in promoting insulin sensitivity and lowering blood sugar levels. The pharmacological mechanisms, bioactive components and scientifically proven usefulness of herbal plants the use of therapeutic plants to treat diabetes are examined in this review, which summarises the most recent research in this area. In terms of managing glucose metabolism, improving insulin sensitivity and protecting pancreatic beta cells, medicinal herbs such as Coccinea indica, Salacia oblonga and Berberis aristae (berberine) have shown efficacy.
Diabetes mellitus, Medicinal plants, Hyperglycaemia, Anti diabetic, Antioxidant.