FREQUENCY : QUARTERLY
PUBLISHER : ANANDI HEALCARE LLP,WASHIM-444505
CHIEF EDITOR : Dr. Prashant Sakharkar
COPYRIGHT : INTERNATIONAL JOURNAL OF PHARMACY AND HERBAL TECHNOLOGY
STARTING YEAR : 2023
SUBJECT : MEDICAL SCIENCES
LANGUAGE : ENGLISH
PUBLICATION FORMAT : ONLINE
PHONE NO : +91 9172954046
EMAIL ID : editorijpht@gmail.com
WEBSITE : www.ijprdjournal.com
ADDRESS : Near Kaleshwwar Mandir Shukrawar peth, Washim-444505 Maharashtra
Author Name: Rohit Bagal *, Sarfraz M. Kazi, Sanjay K. Bais
Email: rohitbagal1213@gmail.com
College: Fabtech College of Pharmacy, Sangola, Maharashtra 2689-2698
This thesis looks at curcumins ability to prevent breast cancer and makes a strong argument for its usefulness in this regard. Phytochemical examination of the selected plant indicates the presence of flavonoids, which have great antioxidant activity and are also known to be helpful in treating cancer. The effects of curcumin and its analogous compounds, including isoeugenol, eugenol orthodimer on cell toxicity. The ability to produce reactive oxygen species and the ability to scavenge radicals, were investigated. The characteristics of curcumin, a yellow pigment found in the rhizome of the Curcuma longa plant, are covered in this article. The review examines various formulation strategies, including the selection of excipients, methods of tablet preparation, and optimization techniques to enhance the bioavailability of curcumin. In vitro and in vivo research that evaluate the anticancer effectiveness of curcumin tablets against different cancer cell lines and animal models are also covered. Curcumins involvement in preventing tumor growth, triggering apoptosis, and regulating inflammatory pathways is highlighted by an evaluation of its pharmacokinetics, safety profile, and mechanisms of action. According to the results, curcumin herbal tablets show promise as an adjuvant therapy for cancer treatment; nevertheless, more clinical research is required to develop standardized formulations and dosing schedules.
Curcumin, Antioxidant, Anti-inflammatory, Curcuma Longa, ROS (reactive oxygen species), Anticancer, Herbal tablet, Phytochemical, Bioavailability, Dosage form, Pharmacodynamic.