Preformulation research involves studying the physicochemical characteristic of novel drug candidates drugs effectiveness a Factors that might affect dosage form development. This research may highlight the need for molecular modification or provide essential information for formulation design. Developing a pharmaceutical formulation requires careful consideration of each drugs unique chemical and physical characteristics. Preformulation refers to studies that examine the physical and chemical characteristics of new drug might impact its efficacy and dosage form development. These studies can indicate the need for molecular modifications or provide valuable insights for formulation design analysis. Preformulation data are essential for understanding potential pharmacokinetics in humans and animals, as well as evaluating the advantages and challenges of process adjustments during large-scale production. Conducting optimal formulation studies helps predict the stability of formulations throughout manufacturing, transport, and storage, ultimately determining the marketed products shelf life.